.EdNote { font-style: italic }.bio { font-size: 10pt; font-style: italic; margin-left: 1.5em; margin-right: 1.5em; }.Kicker { font-weight:bold; text-align:justify; margin-left: 1.5em; margin-right: 1.5em; }.LittleLink {font-size: 10pt; text-align:center; font-weight:bold}.LittlerLink {font-size: 8pt; text-align:center; font-weight:bold}.New { color:navy; background-color:yellow; font-weight:bold }.newquote  { font-family: "Times New Roman", serif; font-size: 12pt; color:black; padding-left: 2em; padding-right: 2em }.Normal { font-family: Arial, Helvetica, sans-serif; font-size: 12pt; color:navy }.quote  { font-family: "Times New Roman", serif; font-size: 12pt; color:black }.Smaller {font-size:80% }ul.SpaceOut > li { margin-bottom:2em}.Special { font-weight:bold; color:#006622; }.SpecialKicker { color:#006622 }.TextLink {text-align:right; font-size:80%}a.plain { text-decoration: none }blockquote { font-family: "Times New Roman", serif; font-size: 12pt; color:black }blockquote.sans { font-family: Arial, Helvetica, sans-serif; font-size: 11pt; color:navy }body { font-family: Arial, Helvetica, sans-serif } dd { font-size: 12pt; color:navy;  margin-top: .5em }div.box { border: solid; border-width: thin; width: 100%; border-color:black; align:center}div.infobox { align:center; background: #DDDDDD; padding: .5em 2em .5em 2em; width: 80%; margin-left: auto; margin-right: auto; border: solid; border-width: 1; border-color:black }div.videobox { color:black; background: #DDDDFF; margin: 0px; padding: 10px;  border-style: outset; border-width: 2; border-color: black }dt { font-size: 12pt; font-weight:bold; color:#006622; margin-top: 2em }h1 { font-size: 24pt; color:brown; font-weight:bold; text-align:center}h2 { font-size: 20pt; color:navy; font-weight:bold; text-align:center}h3 { font-size: 14pt; color:brown; font-weight:bold; font-family: Arial, Helvetica, sans-serif}h4 { font-size: 12pt; color:#006622; font-weight:bold; font-family: Arial, Helvetica, sans-serif;  }h5 { font-size: 12pt; color:navy; font-weight:bold; font-family: Arial, Helvetica, sans-serif; margin-top: 2em }hr { width:100%; height:1; color:gray; background-color:gray; }img {  border-style: none }li { margin-top:.5em }li.big { font-size: 12pt; }li.blk { font-family: "Times New Roman", serif; font-size: 12pt; color:black }li.sub { font-size: 10pt; }ol { font-size: 11pt; font-family: Arial, Helvetica, sans-serif; color:navy }ol.blk { font-family: "Times New Roman", serif; font-size: 12pt; color:black }p { font-family: Arial, Helvetica, sans-serif; font-size: 12pt; color:navy }p.Biblio { margin-left: 4em; text-indent: -3em }p.Ref { font-size: 11pt; margin-left: 2.75em; margin-right: 2em; }p.Update { font-size: 10pt; text-align:center; font-weight:bold; letter-spacing: 4px; margin-top: -20px; color:gray }sup { font-size: 10pt }ul { font-size: 11pt; font-family: Arial, Helvetica, sans-serif; color:navy }ul.big { font-size: 13pt; font-family: Arial, Helvetica, sans-serif;color:navy }/* Tables */table.PharmTable {    font-weight:bold;}table.PharmTable th {    font-size: 14pt;     font-weight: bold;     color: white;     background-color: navy;}table.PharmTable td {    vertical-align: middle;    text-align: center;}table.PharmTable td.subhead {    background-color: #AAA;     color: white;}table.Diseases th {    font-size: 14pt;     font-weight: bold;     color: white;     background-color: navy;    padding: 6pt 0;}td { font-family: Arial, Helvetica, sans-serif; font-size: 12pt; color:navy; vertical-align: baseline; }td.mid  { font-family: Arial, Helvetica, sans-serif; font-size: 12pt; color:navy; vertical-align: middle; }th { font-family: Arial, Helvetica, sans-serif; font-size: 12pt; color:navy; vertical-align: baseline; }.TableHead { font-size: 14pt; font-weight:bold; color: white; background-color: navy;}.TableText { font-size: 12pt; color:#006622; font-weight:bold}